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Semaglutide was administered weekly at the relatively lower doses of 0.25mg/week for the first 4 weeks, and then at 0.5mg/week during weeks 5-8

Based on the SURPASS-2 trial, tirzepatide, when taken once a week in doses of 10 or 15 mg, is more effective in reducing blood pressure than semaglutide, which is taken once a week in a dose of 1 mg