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doi:10.1089/jmf.2022.0042

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FDA-labeled warnings include: Risk of thyroid C-cell tumors (contraindicated in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2) Pancreatitis (report severe abdominal pain, with or without vomiting) Gallbladder disease (including gallstones and cholecystitis) Acute kidney injury secondary to dehydration from gastrointestinal symptoms Hypoglycemia when used with insulin or insulin secretagogues (dose adjustments may be needed) Diabetic retinopathy complications in patients with type 2 diabetes and pre-existing retinopathy Suicidal behavior and ideation (monitor for depression or suicidal thoughts) Intestinal obstruction/ileus (particularly with severe constipation) These medications are contraindicated during pregnancy and should be discontinued at least two months before a planned pregnancy

Other arrangements may be included in future surveys as the market evolves. The survey asks Up to what dollar amount does your firm promise to contribute each year to an employees HRA or health reimbursement arrangement for single coverage? We refer to the amount that the employer commits to make available to an HRA as a contribution for ease of discussion

Effectiveness varies depending on dosage, metabolism, and lifestyle changes