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Dual GLP-1/glucagon receptor agonists, including mazdutide, integrate appetite suppression with increased energy expenditure and fat oxidation, while triple GLP-1/GIP/glucagon agonists, such as retatrutide, further augment these mechanisms through multi-pathway receptor engagement

Due to its impact on the central nervous system and cardiovascular system, certain patient populations are advised to avoid this treatment unless under direct medical supervision

In the current trial, participants took the pill once a day with no food or water restrictions

Animal models and meta-analysis studies on human consumption of lycopene-rich foods support these findings

Most patients report decreased hunger and enhanced satiety whilst taking this medication