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NAD is an enzyme naturally produced by the body that plays a central role in how cells generate energy

For instance, in each of the warning letters to Xcel Research, Prime Vitality, Summit Research, and Swisschem, FDA observed that the companies marketed their products as for research use only, but also observed from the companies websites and social media pages that the companies intended the products to be used by human patients

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This property is why oral administration is discussed alongside injection in the literature, though human bioavailability data via the oral route has not been established