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These rates were defined as the ratio of embryos (or blastocysts) suitable for transfer or cryopreservation based on the number of normally fertilized (2PN) oocytes observed on Day 1 ( Cumulative clinical pregnancy and cumulative live birth rate are defined as the delivery of at least one live birth resulting from the initial oocyte retrieval, including all fresh embryo transfers and any subsequent frozen embryo transfers, until the first clinical pregnancy/live birth delivery or until all embryos are used, whichever occurs first

While subpockets B and C are rather large, subpocket A is narrow and restricted in depth by FAD at the bottom of the pocket, limiting the choice of modifications of the inhibitor in subpocket A

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10.1073/pnas.0407076101 Proc Natl Acad Sci U S A