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Warnings Do not use if under the age of 18, pregnant, or nursing

Experimental approaches include behavioral testing (Morris water maze, novel object recognition), electrophysiology (LTP recording), neurochemical analysis, imaging techniques (PET, MRI), and various neurotoxin or transgenic disease models

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"Gasperi2019 Niacin In The Central Nervous System An Update Of Biological Aspects And Clinical Applications." International Journal of Molecular Sciences , 2019

The OH depolymerizes GI mucin, inactivates pyruvate dehydrogenase, an essential mitochondrial enzyme, and damages mitochondrial RNA and DNA in the GI tract (113)