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Much of this effect was found to be driven by D5 signaling in DCs, which increased the frequency of inflammatory CD4 + T-cells in the CNS and drove inflammation by blocking signal transducer and activator of transcription and inducing the activity of IL-12 and IL-23 in T-cells (Prado et al., 2018)

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It binds to vagal afferent nerve terminals, sending rapid, immediate "stop eating" signals directly to the brainstem

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Jan 27, 2023 What Is Medical Underwriting for Medigap

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Grunert M, et al

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