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The treatments enhanced tear secretion compared to controls, indicating better ocular surface hydration
doi: 10.2119/molmed.2012.00332
lining=leaky gut
Ruiz de Gordoa JC, Bustamante M, Arranz J, Virto M, Barrn LJR, Beltrn de Heredia I, Amores G, Abilleira E, Njera AI, Ruiz R, Albisu M, Prez-Elortondo FJ, Mandaluniz N
These results reveal the dynamic interplay between the structural states of the CRL4 DET1-COP1 E3 ligase complex and its substrate specific activation mechanism, offering mechanistic insights into ubiquitination regulation and a basis for future studies on E3 ligase dynamics
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