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Conventional L-amino acid peptides of this size are degraded within minutes by serum proteases

Hold reconstituted solution at 2-8C and prepare single-use aliquots rather than repeatedly accessing one stock

Most manufacturers recommend refrigeration at 2-8C even for unopened vials, though some formulations remain stable at room temperature for short periods

doi:10.1186/s12958-018-0346-x

It inhibits the production of pro-inflammatory cytokines (TNF-alpha, IL-6, IL-12), modulates the polarization of macrophages towards the M2 (anti-inflammatory) phenotype, and stimulates collagen production in models of pulmonary and cutaneous fibrosis