This protective action works alongside its lightening effects
[PubMed: 21112196] (Summary of approaches to insure the safety of kava, including licensing cultivars, use of peeled and dry roots only, aqueous extraction, limitations on dose and quality of kavalactones, further research and quality control)
Supplementary Information Additional file 1: (download DOCX Supplemental table 1
Proceedings of a WHO technical consultation held 18-21 October, 2005, in Geneva, Switzerland
investigated the warm and cold types of AIHA (wAIHA and cAIHA, respectively) and demonstrated that eryptosis is predominantly driven by cold IgM and/or IgA antibodies rather than warm IgG autoantibodies, as shown by increased PS exposure in response to autoantibodies [329]