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, L-(L-carnitine orotate) 1 .According to another aspect of the present invention, there is provided a pharmaceutical composition comprising the above-described crystalline polymorph Form 1 of L-carnitine orotate of the present invention as an active ingredient, Which comprises administering a therapeutically effective amount of a compound of formula , , , , , , (, B ) .The liver disease to which the composition of the present invention is applied includes various liver diseases known in the art due to excessive stress, drinking, smoking and environmental pollution caused by various pollution

Fifty size-matched islets were perifused with Krebs-Ringer bicarbonate buffer (KRB) containing 0.1% bovine serum albumin at 37 C and 200 L/min

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