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[76] Combined intraperitoneal administration of vitamin C (1g/kg) and vitamin K (10 mg/kg) given prior to chemotherapy increased survival and the effect of several chemotherapeutic agents (cyclophosphamide, vinblastine, doxorubicin, 5-fluorouracil, procarbazine, and asparaginase) in a murine ascitic liver tumor model

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Oncogene 29 , 356367 (2010)

This is where we find ourselves today in the controversy of using these medications as many doctors are using much higher doses than are safe or even required for healthy weight loss