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For pharmaceutical companies, understanding the FDA's regulations regarding off-label use and marketing is critical to avoid potential legal pitfalls
Further complicating the impact of this disease, mild and moderate hypertension are usually asymptomatic, and their presence (and the subsequent increase in cardiovascular risk) is often unrecognized
Some estimates suggest that perimenopausal women make up the majority of users
We evaluated for any potential behavioral side effects such as anxiety-like behavior or repetitive behaviors with MT-II in the normal C57BL/6J mice given the known role of acute MC4R stimulation in increasing stress behaviors in rodents
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