View source 03Sikiric P, Udovicic M, Barisic I, et al
First, the route was intraventricular in rabbits , bypassing the blood-brain barrier entirely
In the preclinical literature it is described across six complementary axes: angiogenesis via VEGFR2/eNOS/NO, regulation of FAK-paxillin signalling, protection of the endothelium and the gastric-intestinal mucosa, modulation of the brain-gut axis with the NO pathway, tendon maturation with fibroblast proliferation, and cytoprotection as a common denominator
Preliminary clinical effect evaluation of resveratrol in adults with allergic rhinitis
[1] Other rare side effects noted (mostly in older literature or high-dose use) include: polycythemia vera and peripheral vascular thrombosis in patients receiving repeated injections (though these associations are not well understood, they were listed in prior product literature as possible adverse events)