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, Rabbani N., and Thornalley P

Oral GLP-1s may reduce some of the complexity that drove past bottlenecks

For example, combination therapies involving linagliptin and alogliptin benzoate, both dipeptidyl peptidase-4 (DPP-4) inhibitors, were omitted as they primarily target the Protein Digestion and Absorption pathway, which was not part of the comorbidity network and thus did not contribute to the network-based impact analysis

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The PGC-1 coactivators promote an anti-inflammatory environment in skeletal muscle in vivo