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Skin and anti-aging focus: Moderate doses (10 to 15 units daily) over longer cycles (12 weeks) allow gradual collagen remodeling without aggressive tissue repair effects

doi: 10.1111/j.1349-7006.2010.01684.x 134 KuligPBurkhardSMikita-GeoffroyJCroxfordALHvelmeyerNGylvsziGet al

Response came within a few hours with full documentation

Asterisks indicate significant difference (P0.05) from control values, # indicate significant difference (P0.05) from ASA treated group and indicate significant difference (P0.05) as compared to BSO+ASA treated group

The water itself doesn't "go bad" in a dramatic way, but you can no longer rely on the manufacturer-validated preservative activity