What they do know is that the slowed gastric emptying creates a cascade of downstream effects
It additionally targets the glucagon (GCG) receptor, another part of the machinery to control blood glucose levels in line with energy expenditure
Studies of embryos created through IVF illustrate the scale of this decline: if you're in your early 20s, roughly 20% of your eggs carry chromosomal abnormalities, rising to about 40% by age 35, roughly 60% by age 40, and over 80% by age 43. These chromosomal errors, most commonly aneuploidy, are the primary reason that fertility declines with age, that miscarriage rates increase, and that conditions such as Down syndrome become more common in pregnancies conceived later in life
This data supports the product's launch in 2014 as the first approved GLP-1 weight loss drug
And as it goes down, the opposite should happen