Melasma is a very common skin condition that causes dark, irregular patches, generally on the face
Brand-name Wegovy and Zepbound are priced at the national level (list price over $1,000 per month) but patients with qualifying employer coverage pay a fraction of that after insurer negotiation and prior authorization
Victor-Vega C, Desai A, Montesinos MC, Cronstein BN (2002)
Ca 2+ is not metabolized and an overload of mitochondrial Ca 2+ may break down the electrochemical proton gradient resulting in a deficit of ATP followed by necrosis [89]
In March 2024, the FDA further approved Wegovy to reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) in adults with established cardiovascular disease and either obesity or overweight