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MEDI0382, a GLP-1 and glucagon receptor dual agonist, in obese or overweight patients with type 2 diabetes: a randomised, controlled, double-blind, ascending dose and phase 2a study
Cell-culture studies use micromolar concentrations on cultured cells
Symptoms of a Sluggish Metabolism: Easy weight gain, difficulty losing weight, low energy, and feeling cold
This is primarily relevant for HSC70 (Roperto, 2022), although BAG3 has also been shown to associate with HSPA1A, increasing its activity (Colvin et al., 2014)