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We are encouraged by the robust reductions in liver fat content and abdominal adipose tissue observed with all three doses of tirzepatide in this population of adults with type 2 diabetes and elevated liver fat content. SURPASS-3 was a 52-week, multi-center, randomized, phase 3, open-label trial evaluating the efficacy and safety of tirzepatide compared to titrated insulin degludeci in adults with type 2 diabetes who have inadequate glycemic control on stable doses of metformin with or without an SGLT-2 inhibitor

TRIUMPH-4 y sus ensayos hermanos tambin introducen un nuevo brazo de dosis de mantenimiento de 4 mg, que se est evaluando junto a 9 mg y 12 mg

Shoieb AM, Hahn KA, Van Laack RL, Barnhill MA

These include lifestyle modification requirements (69%), trialing lower-cost medications first (63%) and limiting therapy duration (63%)