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Semaglutide (Wegovy): A typical start is 0.25 mg a week for the first month

For September, I began using the higher concentration but reduced it from 20 units down to 10 units for September 3 and September 10

Gastrointestinal symptoms are typically the most prominent and may include: Severe nausea and vomiting that persists despite usual remedies Intense abdominal pain or cramping Diarrhoea which may worsen dehydration Loss of appetite beyond normal medication effects Bloating and feeling of fullness due to significantly delayed gastric emptying These digestive symptoms occur because semaglutide slows the movement of food through the stomach, and excessive doses amplify this effect considerably

doi: 10.1016/j.numecd.2021.08.049, 34

Likewise, declining hormone levelsespecially estrogen, progesterone, testosterone, and DHEAcan worsen gut permeability (leaky gut), increase visceral fat, and negatively affect insulin sensitivity