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The survey data found lower back pain among the symptoms showing significant improvement, which suggests that for many patients, the net effect is positive despite potential side effects

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The SURPASS clinical trial program established tirzepatides efficacy profile across type 2 diabetes populations, demonstrating superior HbA1c reduction and weight loss versus comparator GLP-1 agonists including semaglutide

Kimberly Gudzune, medical director of the American Board of Obesity Medicine

That includes patients with severe obesity, significant metabolic disease, or a history of losing and regaining weight repeatedly