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To infer whether the observed changes in transcriptional gene programmes indicative of reduced synaptic plasticity by GIPR antagonism and GLP-1R agonism in the DVC translate to altered signalling in the hypothalamus, we performed a cellcell communication analysis using the LIANA+ 49 implementation of the CellPhoneDB 50 algorithm, and the receptorligand database from NeuronChat 51 (Fig

Many patients choose SRT because it offers peace of mind without the anxiety of surgery

The trifecta of satiating nutrients is protein, fat, and fiber

No head-to-head trial exists

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