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PT-141, also known as bremelanotide, is a synthetic derivative of alpha-melanocyte-stimulating hormone

Here, we primarily discuss GLP-1RAs that are currently approved and under consideration for MASLD, along with some co-agonist strategies showing promising results

It is linked to elevated levels of fibrinogen and C-reactive protein, diabetes, insulin resistance, dyslipidemia, and hypertension, all of which raise the risk of CVD events ( It is less evident how GLP-1 agonists directly affect arrhythmias, some studies suggest they may reduce frequency of arrythmias because their favorable effects on metabolism and over all cardiovascular health

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(2) serum IGF-1 and IGFBP-3 levels as a baseline biomarker anchor