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When the research question specifically isolates these two mechanisms, adding GHK-Cu introduces confounding from its gene-expression and anti-inflammatory effects
Keatings lab spent many years designing peptides that would bind to the section of Mcl-1 involved in this interaction but not to other members of the protein family
Its mechanism is studied alongside related research compounds such as TB-500
The peptide typically remains stable for 30-45 days when refrigerated
Nicotinamide N-methyltransferase (NNMT), is a naturally occurring enzyme involved in fat accumulation and energy metabolism, is inhibited by it (1)
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