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Identification of genetic determinants and enzymes involved with the amidation of glutamic acid residues in the peptidoglycan of Staphylococcus aureus

Sci Rep 6:23010

Two novel monothiol glutaredoxins from Saccharomyces cerevisiae provide further insight into iron-sulfur cluster binding, oligomerization, and enzymatic activity of glutaredoxins

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Second, cancer cells are highly adaptable and can activate compensatory antioxidant pathways, like the thioredoxin system, to survive GSH inhibition, reducing therapeutic effectiveness