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10.1186/s12951-024-02606-1 Summary Keywords erythrocytes, hypoxia, nitric oxide, adenosine, Cys93, drug delivery systems, RBC eNOS, CYB5R3 Citation Xu Y, Yu Z, Liu H, Bian X and Tang W (2025) Erythrocytes enhance oxygen-carrying capacity through self-regulation

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Preclinical studies indicate potential roles in: Supporting healthy fat metabolism and reduction of adipogenesis Improving insulin sensitivity in metabolic research models Enhancing NAD+ salvage pathway efficiency Exploring effects on energy homeostasis and longevity pathways These findings remain preliminary and confined to laboratory and animal models