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Eligibility is determined after clinical evaluation and labs

Randomization and masking Randomization (1:1) to semaglutide 2.4 mg or placebo was done centrally by the clinical research organization (Parexel) in a double-blind manner using an interactive web-based response system (IWRS) with a fixed-size blocking schema, without stratification

Manufacturer Novo Nordisk has also submitted a 7.2mg single-dose device to the MHRA that would deliver the full dose in one injection

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GLP-1 receptor agonists like liraglutide and semaglutide are popular weight loss tools for people with diabetes, obesity or excess body weight