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262,263 Hypogonadotropic hypogonadism is a condition marked by levels of gonadotropins (LH and FSH) that are too low to support normal ovarian function

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In contrast, chronic heavy or binge drinking induces compensatory downregulation of GABA_A receptor subunits, altered receptor trafficking, and reduced inhibitory neurotransmission, culminating in neuronal hyperexcitability and heightened vulnerability to excitotoxic neuronal damage [42,76]

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However, there may be relatively weak experimental evidence as to why it is not more widely used as an adjunct in cancer therapy or generates little interest from pharmaceutical companies