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Participants were prescribed a reduced-calorie diet (500-kcal/d deficit relative to estimated energy expenditure calculated at week 0) and increased physical activity (150 min/wk), recorded daily by participants (using paper diaries, apps, or other tools) and reviewed during counseling visits

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The Significance of Lifestyle Changes Diet and Nutrition While semaglutide can aid in appetite suppression, it is not a replacement for a healthy diet

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