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As of the time of writing, retatrutide has not been granted a marketing authorisation by the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA)

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Hydrogen and methane production reflect microbial fermentation over a period of time

Importantly, the compound reportedly avoided the nausea and gastrointestinal side effects commonly associated with many first-generation GLP-1 therapies, a factor that could become increasingly important as patient adoption expands

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