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The compound has been characterized in rat and mouse cognitive-research models principally scopolamine-induced cognitive impairment, aged-rat cognitive decline, and the APP/PS1 transgenic Alzheimers disease model with reported effects on hippocampal synaptogenesis, dendritic spine density, and Morris water maze performance

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Neutralizing activity of Nb1_gbHSV The bound epitope spread over different domains that are close in prefusion conformation indicates that the neutralizing activity is achieved by preventing gB from undergoing the necessary conformational changes for the fusion process

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