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Given the characteristics of short-lived free radical species, which are challenging to confirm as transferring between cells through gap junctions after APAP overdose, we employed a thioacetamide-induced hepatotoxicity model

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Andrologia (2019) 51(6):e13263

Although the carboxylate group of the E residue of GSH makes no direct contacts with the I site, other portions of the residue contact D150 (protomer B) and, indirectly, R227 (protomer A) at the inter-protomer interface (Figs