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They are signal sequences of PhoA [6] , LTB [7] , and StII [8] , named signal peptide 1 (SP1), signal peptide 2 (SP2), and signal peptide 3 (SP3), respectively

Cho SK, Pedram A, Levin ER, Kwon YJ

If you take certain medications: Talk with your clinician before taking berberine if you take medications, including diabetes meds or insulin, anticoagulants or antiplatelets, or drugs metabolized by CYP3A4/P-gp

Shrink fat-cell size adipocytes tend to store less and burn more, trimming hypertrophy (seen in rodent/adipocyte studies)

Conflict of interest FB: NovoNordisk and Boehringer-Ingelheim, advisor/consultant/speaker