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The main classes of carotenoids are carotenes (as beta-carotene, alpha-carotene, and lycopene) and xanthophylls (as lutein, zeaxanthin, and canthaxanthin) 38,41

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Thomas Gates, then McNeils medical director, shot off a memo to the chief executive of Johnson & Johnson, the president of McNeil and other top officials, laying out a detailed plan of action for diffusing media interest in the research and limiting the extent and duration of the coverage. Gates envisioned two possibilities: Low Level of Publicity (most probable scenario) and High Level of Publicity (worst case scenario). For the latter, Gates suggested a series of responses: a letter-writing campaign to medical societies, doctors, pharmacists and academics

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