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The Direct Effects on the Heart As more research comes out on the effects of vaping, we have seen that many vape products can increase blood pressure and the secretion of adrenaline around the body

We also excluded North Carolina from the results because the state plays a central role in the model as a major source of illicitly trafficked cigarettes

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The agency has also provided resources to retailers to improve compliance with tobacco laws and regulations, including a voluntary education program called "This is Our Watch," which offers free resources to help retailers calculate the age of customers, including a digital age verification calendar and an age calculator app

Statistical analysis Data analyses were conducted using SAS 9.4 (SAS Institute, Cary, North Carolina, US)