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This gradual escalation allows your body to adjust to the medication and helps identify the dose that balances effectiveness with tolerable side effects

Nat Rev Endocrinol 19(3):164176 Perdomo CM, Cohen RV, Sumithran P et al (2023) Contemporary medical, device, and surgical therapies for obesity in adults

Body composition can shift during a taper even when weight is relatively stable, and tracking measurements helps distinguish true weight maintenance from a shift toward fat gain with muscle loss that the scale might miss

Weghuber, D., Barrett, T., Barrientos-Prez, M., Gies, I., Hesse, D., Jeppesen, O

The initial correlation analysis revealed that gender, age, baseline body mass index, diabetes duration, and chronic comorbidities showed no significant association with muscle mass loss