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Available clinical evidence regarding L-carnitine supplementation in MASLD is summarized in Table 2, highlighting both reported metabolic benefits and the current limitations and heterogeneity of human studies

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older, non-selective agents are available for different routes of administration [i.e., oral (PO), intramuscular (IM), and intravenous (IV)] and continue to be investigated actively (Pereira and Goudet, 2019)