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"Just replacing your source of nicotine is not the key here." He noted that most smokers who tried e-cigarettes to quit didn't use high-nicotine vapes

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The CHRNA4 gene rs1044396 polymorphism was genotyped by real-time quantitative polymerase chain reaction (PCR) using TaqMan (C__25765540_10) (Applied Biosystems, CA, USA) and Rotor-Gene Q (QIAGEN, SP, Brazil)

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