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Pharmacological studies have confirmed that anti-inflammatory and immunomodulatory effects were mainly found in 14- and 15-membered ring macrolides, such as EI and AZI [63], which may explain why SPI showed no obvious effects on CS-induced airway epithelial barrier dysfunction

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This is probably because smoking and vaping offer the most potent effects when compared to other methods

This result indicates that diet-dependent factors contribute to weight loss triggered by nicotine treatment

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