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However, because semaglutide slows digestion, women should take extra care to follow the instructions for their birth control pills

Clinical trials show that some patients experience mild to moderate blood pressure reduction, though severe hypotension remains uncommon when treatment is properly monitored

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Notably, a clinical study demonstrated that T2DM patients receiving insulin therapy experienced significantly higher rates of pancreatitis compared to those treated with GLP-1RAs, and notably, no pancreatitis cases have been reported in clinical trials of the novel GLP-1RA Cotadutide, indicating that a comprehensive risk assessment of GLP-1RAs for pancreatic cancer remains premature pending additional data on these novel medications [8]