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In this June 27, 2018 photo, a mother and her daughter walk past a coffee shop displaying a sign saying 'Complete separation of smoking areas: Non-smoking and Smoking' in Tokyo

Each hit of nicotine floods the brains receptor sites, overstimulating them until the neurons adapt by making more of those receptors and reducing their sensitivitya process known as upregulation

This latency period may contribute to elevated risk with increasing age

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