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In the review of 22nd Centurys MRTP applications, the FDA found that nicotine levels in tobacco and mainstream smoke of VLN cigarettes are at least 96% lower than the majority of marketed and market-leading conventional cigarette brands
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The FDAs proposed menthol rule relies heavily on a study published in 2021 projecting that a federal ban would avert about 650,000 premature deaths by the year 2060, demonstrating a substantial benefit to public health
METHODS Study design We conducted a cross-sectional online survey of targeted convenience sampling of e-cigarette users in the United States in January 2022 through Prolific , using self-administered questionnaires to collect data
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