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In 1910, MacDonald started at Biograph and was an actor and director at a variety of early film studios, including Imp, Triangle, Sennett, and Pathe

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Chandler pushed back on that assertion, saying that research does not show that adults who switch to an e-cigarette product are more likely to quit -- and that it also shows that those who use e-cigarettes often use both products

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doi:10.1002/14651858.cd008286.pub3