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The DMF protects healthy and vitiligo melanocytes against monobenzone-induced toxicity via Nrf2 activation, demonstrating its therapeutic potential in vitiligo treatment ( 7 Conclusion Complementary herbal therapies have gained attention as an adjunct approach in treatment of vitilio

Smoking cigarettes involves a substantial amount of free radicals that may degrade exogenous and endogenous antioxidants, as well as dysregulate monocytes and vascular smooth muscle cells [70] Endothelial nitric oxide synthase (eNOS)- derived nitric oxide plays a crucial role in regulating platelet accumulation, vasodilation, and maintaining stability between smooth muscle cell growth and proliferation