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Specifically, a recent retrospective study showed that GLP-1RAs plus metformin were superior to metformin alone in improving ED, regardless of different background characteristics of patients ( Multiple biological mechanisms are hypothesized to mediate the potentially beneficial role of GLP-1RAs in ED development ( Figure 5 ), such as induction of positive vascular effects and weight loss

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Lancet Diabetes Endocrinol 7(10):776785 Vilsbll T, Christensen M, Junker AE, Knop FK, Gluud LL (2012) Effects of glucagon-like peptide-1 receptor agonists on weight loss: systematic review and meta-analyses of randomised controlled trials

The standard route in research community use and in most published guides

It is important to note that oral semaglutide is not suitable for individuals with type 1 diabetes or diabetic ketoacidosis