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The gentler throat hit enables higher absorption than freebase without the harshness, mimicking the nicotine delivery of traditional cigarettes more closely

This can affect treatment and lead to further health complications

For these reasons, individualized guidance from a mental health professional is essential

Supplementary analysis In a supplementary analysis, we re-estimated the fully adjusted model using current cigarette smoking only as the reference group to assess whether current exclusive e-cigarette use was associated with lower odds of hypertension relative to current smoking

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