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There are two types of nicotine dependence you should know: Physical dependence : This type of dependence occurs when your body requires nicotine to avoid withdrawal symptoms

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Recent meta-analyses found a borderline significant association between PARP1 Val762Ala polymorphism and overall cancer risk, although after stratification by cancer types, the polymorphism could predispose to gastric cancer, thyroid cancer and cervical cancer, in an Asian population, but not in Caucasian and African populations (109, 110)

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