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The histamine released causes blood vessel dilation (redness), increased vascular permeability (swelling), and nerve ending stimulation (itching and pain)

Liposomal delivery systems encapsulate AHK-Cu in lipid spheres, potentially improving penetration through the stratum corneum and protecting the peptide from degradation

TRPV1: on the road to pain relief

Feb 27 2020;20(5)doi:10.3390/s20051288 Signorelli SS, Platania I, Tomasello SD, et al

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