Besides nicotine, cigarette smoke contains more than 5,000 harmful chemicals, with at least 69 of them causing cancer
Its a pretty big change
Hammond and colleagues found increased rates of e-cigarette use among adolescents in Canada, the US, and the UK (from 2017 to 2018) but increased rates of combustible cigarette smoking only among Canadian adolescents, which, as per the authors conclusions, suggests that e-cigarette use may not be causally related to increased smoking uptake.[3] E-cigarettes may indeed be a gateway to combustible cigarette smoking, and this is a valid concern, but there is not yet enough evidence to state a conclusive causal association
While the tobacco industry was vehemently denying that there was any causal connection between smoking and disease, individual cigarette companies reacted to the unwelcome suggestion by introducing and advertising new brands of filter cigarettes, which, the television advertising for them implied without actually talking about health, were somehow a lot more beneficial, or somehow less harmful, to smokers than unfiltered cigarettes
"Science of Transgenic Cotton"
